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five–4 μmol/L selection,[156][157] the concentration of serotonin in synaptic vesicles was measured at 270 mM.[182] subsequent vesicular release, the ensuing focus of serotonin from the synaptic cleft, to which serotonin receptors are exposed, is believed to be about three hundred μmol/L. As a result, whilst in vitro receptor binding affiniti